Madecassoside sits in the soothing category, but the reason it works is specific. Terpenoid from Centella Asiatica; inhibits NF-kB; stimulates TGF-beta for collagen.

The scientific name is Madecassoside. Terpenoid from Centella Asiatica; inhibits NF-kB; stimulates TGF-beta for collagen. This mechanism is consistent across properly formulated products, which means the real variable is concentration and delivery system.

Typical working concentration is 0.1–0.5%. Best suited to sensitive, acne-prone, post-procedure skin. Primary applications: wound healing, anti-inflammatory, soothing, collagen.

Works well with: Centella asiatica, ceramides, hyaluronic acid.

Key active compound of Cica; now formulated as isolated ingredient.