Urea is primarily used for hydration, exfoliation (high %), barrier repair, itch relief. The mechanism: Part of NMF; at low % = humectant; at high % = keratolytic (dissolves protein bonds in dead skin).
The scientific name is Urea. Part of NMF; at low % = humectant; at high % = keratolytic (dissolves protein bonds in dead skin). This mechanism is consistent across properly formulated products, which means the real variable is concentration and delivery system.
Typical working concentration is 5–10% (hydrating); 20–40% (keratolytic). Best suited to dry, eczema, very dry/thickened skin skin. Primary applications: hydration, exfoliation (high %), barrier repair, itch relief.
Works well with: Ceramides, hyaluronic acid, lactic acid.
Naturally in skin’s NMF; concentration determines whether it hydrates or exfoliates.